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| Macé, Sabrina; Truelstrup Hansen, Lisbeth; Rupasinghe, H. P. Vasantha. |
| Background: Worldwide, Streptococcus pyogenes is the leading cause of bacterial pharyngitis. To reduce the use of antibiotics, antimicrobial phytochemical-containing remedies, which have long been in use in traditional medicine, may provide new approaches for management of streptococcal pharyngitis. The objective of this study was to assess the inhibitory activities of 25 natural phenolic compounds against three strains of S. pyogenes. Methods: After an initial screening, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the nine most effective phenolic compounds were determined. The effect of four compounds with the lowest MIC and MBC on streptococcal growth and biofilm formation was also studied. Results:... |
| Tipo: Text |
Palavras-chave: Pharyngitis; Strep throat; Biofilm; Naphthoquinone; Infection; Disease; Polyphenols. |
| Ano: 2017 |
URL: https://archimer.ifremer.fr/doc/00603/71515/69934.pdf |
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| CAVALCANTI,PAULO M.S.; MARTINS,MARIA DO CARMO C.; NUNES,PAULO H.M.; ALVES FILHO,FRANCISCO C.; SILVA,JANYERSON D.P.; CAVALCANTI,SUZANA M.G.. |
| Abstract This study investigated the effects of the ethanolic extract from the bark of Combretum leprosum (ECL) on intestinal transit and castor-oil induced diarrhea in mice. The oral administration of ECL (750 and 1000 mg/kg) slowed intestinal transit (ID50 of 455 mg/kg). The ECL (250-1000 mg/kg) reduced castor-oil induced diarrhea, in a time- and dose-dependent manner (p < 0.05). To determine if antidiarrheal effect of ECL involves α2-adrenergic or opioid receptor activation, the mice were pretreated with antagonists of these receptors, yohimbine or naloxone respectively. None of these drugs inhibited the antidiarrheal effect of ECL. To test if antidiarrheal effect of ECL is due to an antisecretory action, we realized the enteropooling assay on rats.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Combretum leprosum; Antidiarrheal effect; Medicinal plants; Polyphenols; Intestinal transit; Enteropooling. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000100701 |
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| Zeoula,Lucia Maria; Machado,Erica; Carraro,Jocasta; Aguiar,Sílvia Cristina; Yoshimura,Emerson Henri; Agustinho,Bruna Calvo; Santos,Fabio Seiji dos; Santos,Nadine Woruby. |
| ABSTRACT The objective of this study was to evaluate the effect of adding ground soybeans and antioxidants to diet of buffaloes on intake, ruminal microbial production, total and ruminal digestibility of nutrients, and ruminal fermentation parameters. Four crossbred buffaloes with a mean weight of 506±29 kg were distributed in a 4×4 Latin square. Four diets were tested: control; diet with ground soybeans; diet with ground soybeans and supplementation with yerba mate; and diet with ground soybeans and supplementation with yerba mate and vitamin E. The addition of ground soybeans had negative effects on intake of dry matter, organic matter, crude protein, neutral detergent fiber, and acid detergent fiber, as well as ruminal digestibility of neutral detergent... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ether extract; Polyphenols; Ruminal manipulation; Ruminal metabolism; Tocopherol. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982019000100709 |
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| Fellenberg,MA; Espinoza,A; Peña,I; Alarcón,J. |
| The nutritional and sensorial characteristics of chicken meat can be affected by oxidative rancidity, process of oxidation of lipids in the meat that constitutes one of the main forms of food deterioration. This problem may be prevented or reduced by adding antioxidants to the meat during the process of marination. In the present study, the addition of a polyphenol-rich quillay extract (QLPerm®) at 5 levels (0, 0.05, 0.10, 0.15, and 0.20%) to the marinade of chicken meat was evaluated. The marinated meat was stored under refrigeration (6 ºC) for 0, 2, 4, 6, and 8 days. Basal and induced lipid oxidation was evaluated by TBARS analysis. Microbiological quality was assessed by total coliforms and mesophillic aerobe counts. The application of this natural... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Broiler meat; Lipid oxidation; Marinade; Polyphenols; Quillay. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2011000100011 |
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| Souza,Kellina Oliveira de; Moura,Carlos Farley Herbster; Brito,Edy Sousa de; Miranda,Maria Raquel Alcântara de. |
| Information on antioxidant properties at different ontological stages may help producers and food technologists to identify which cultivar and/or maturity stage are most adequate for their need, therefore this work aimed to study the changes in the antioxidant metabolism during acerola development. Fruit from cv. Flor Branca, BRS366 and Florida Sweet were harvested at different stages: immature green colored (I), physiologically mature with green color and maximum size (II), breaker (III) and full red ripe (IV). After harvest, fruits were selected, divided into four replications with 500 g each and evaluated regarding their titratable acidity, pH, soluble solids, total soluble sugar, vitamin C, polyphenol, anthocyanin, yellow flavonoid, total antioxidant... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Malpighia emarginata; Development; Vitamin C; Enzymes; Polyphenols. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-29452014000200004 |
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| Hyogo,Akiyo; Kobayashi,Toshihiro; Garcia del Saz,Eva; Seguchi,Harumichi. |
| Human neutrophils stimulated by phorbol myristate acetate (PMA), an activator of protein kinase C, produce active oxygen by NADPH oxidase in intracellular structures. We added succinimidyl ester of dichlorodihydrofluorescein diacetate (H2DCFDA), which first emits fluorescence when oxidized with active oxygen species, to neutrophils to produce active oxygen, in order to investigate the antioxidant effects of protocatechuic acid, ferulic acid, and caffeic acid which belong to polyphenols and are widely distributed among plants. Particularly, we focused on examining whether these substances capture and eliminate active oxygen inside or outside the neutrophil cytoplasm and whether these substances inhibit NADPH oxidase. Fluorescence microscopy demonstrated... |
| Tipo: Journal article |
Palavras-chave: Antioxidant effects; Polyphenols; Human neutrophils; Flow cytometry. |
| Ano: 2010 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000300040 |
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| Ortiz-Robledo,Faviola; Villanueva-Fierro,Ignacio; Oomah,B. Dave; Lares-Asef,Ismael; Proal-Nájera,J. Bernardo; Návar-Chaidez,J. Jesús. |
| Oat (Avena sativa L.) is a cereal grain, its seeds are rich in nutrients, is consumed as whole grain with health benefits fot humans due to its antioxidants, such as the avenanthtamides (Avns). The contents of Avns 2c, 2f and 2p were evaluated by HPLC in groats and hulls of oat varieties Chihuahua, Cuauhtemoc, Raima and Avemex cultivated in Durango, México. The association of these Avns with protein, fat, crude fiber and ash of oat was also investigated. A 4x2 bifactorial design was used, with the number of varieties and groats ot hulls as factors. Avns contents differed significantly (p<0.05) among oat varieties, groats and hulls. Avemex groats had the highest concentrations of Avns: 3.6±0.7, 3.0±0.5 and 3.3±0.6 mg kg-1 fot 2c, 2f and 2p Avns. Avemex... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidants; Groats; Hulls; Oat; Polyphenols. |
| Ano: 2013 |
URL: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1405-31952013000300002 |
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| Lopes,Mônica Maria de Almeida; Miranda,Maria Raquel Alcântara de; Moura,Carlos Farley Herbster; Enéas Filho,Joaquim. |
| Lately, tropical fruit consumption has increased due to a higher knowledge of its nutritional and therapeutic value. The aim of this work was to evaluate the antioxidant potential of cashew apples from different early dwarf clones during their ripening. The clones analyzed included: CCP 76, CCP 09, BRS 189 and BRS 265 in seven ripening stages. They were analyzed for vitamin C, total carotenoid, total anthocyanin, yellow flavonoids and polyphenol content and total antioxidant capacity. Clone BRS 265 ripe cashew apple presented the highest vitamin C content (279.37 mg x 100 g-1). The ripe BRS 189 cashew apple is colored bright red, and its total anthocyanin content was the highest (21.16 mg x 100 g-1). The yellow flavonoids content was higher for ripe CCP 76... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Polyphenols; ABTS; Vitamin C; Carotenoids; Food analysis. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-70542012000300008 |
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| GRANDE-TOVAR,CARLOS D.; JOHANNES,DELGADO-OSPINA; PUERTA,LUISA F.; RODRÍGUEZ,GLORIA C.; SACCHETTI,GIAMPIERO; PAPARELLA,ANTONELLO; CHAVES-LÓPEZ,CLEMENCIA. |
| Abstract: Ackee (Blighia sapida K. D. Koenig) is an exotic fruit widely consumed in the Caribbean countries. While there is extensive research on the presence of hypoglycin A, other bioactive compounds have not been studied. We identified and quantified the changes in bioactive molecules (total phenol, ascorbic acid, hypoglycin A, squalene, D: A-Friedooleanan-7-ol, (7.alpha.), and oleic acid), antioxidant potential, and volatile compounds during two stages of ripe. A clear reduction in hypoglycin A, ascorbic acid, and total polyphenols during the maturation process were observed. On the contrary, oleic acid, squalene, and D: A-Friedooleanan-7-ol, (7.alpha.) contents increased about 12, 12, and 13 times, respectively with advancing maturity. These bioactive... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidants; Friedooleanan; Hypoglycin; Polyphenols; Squalene. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000500616 |
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| BATISTA,Marisa Cristina Aranha; ABREU,Bruno Vinicius de Barros; DUTRA,Richard Pereira; CUNHA,Mayara Soares; AMARAL,Flavia Maria Mendonça do; TORRES,Luce Maria Brandão; RIBEIRO,Maria Nilce de Sousa. |
| ABSTRACT Geopropolis, a mixture of plant resin, wax, soil and salivary secretion, is produced by the stingless bee Melipona fasciculata. This aim of this study was to investigate the chemical composition and antioxidant activity of geopropolis collected from beehives in two phytogeographical regions, flooded fields and cerrado, in the municipalities of Palmeirândia and Fernando Falcão, Maranhão State, northeastern Brazil. The geopropolis compounds were identified by gas chromatography-mass spectrometry (GC/MS). Additionally, total phenolic content was determined with the Folin−Ciocalteu reagent and antioxidant activity was evaluated in vitro by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays. The four geopropolis... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Stingless bee; Polyphenols; Triterpenes; Phytogeographical regions. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672016000300315 |
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| Kobus-Cisowska,Joanna; Szymanowska,Daria; Szczepaniak,Oskar Marek; Gramza-Michałowska,Anna; Kmiecik,Dominik; Kulczyński,Bartosz; Szulc,Piotr; Górnaś,Paweł. |
| ABSTRACT: The aim of this study was to examine the impact of cultivar and spear color on the composition of polyphenols in asparagus spears (Asparagus officinalis). The five genotypes (Schwetzinger Meisterschuss, Huchel’s Alpha, Gijnlim, Grolim and Eposs) and three growing conditions of asparagus spears (Asparagus officinalis) were investigated. The polyphenols were determined by applying the HPLC-DAD system. The obtained results were subjected to the principal component analysis. Among the analyzed asparagus samples cv. Grolim contained the highest amounts of phenolic acids and flavonols. The varied quantitative and qualitative composition of polyphenolics resulted most probably from changes occurring during vegetation, such as a lack of access to light... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Asparagus cultivars; Antioxidative activity; Flavonols; Phenolic acids; Polyphenols. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019000400751 |
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| Bisognin,Dilson Antônio; Luz,Leandro Vinícius da; Lencina,Kelen Haygert; Santos,Clarissa Obem dos; Sautter,Cláudia Kaehler. |
| Abstract: The objective of this work was to evaluate different solvents and times in the ultrasound-assisted extraction of polyphenols, in order to quantify the total phenolic and flavonoid contents in and the antioxidant activity of mate (Ilex paraguariensis) leaves. The experiment was carried out in a completely randomized design, in a 8x3 (solvent x time of extraction) factorial arrangement. The solvent extractors were distilled water and aqueous solutions of ethanol, acetone, and methanol, acidified or not with hydrochloric acid, and the time of ultrasound-assisted extractions were 15, 30, and 45 min. All extractions were finished with a mechanical agitation of 30 min. Samples treated with acidified hydroalcoholic solvents resulted in higher values of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mate; Polarity; Polyphenols; Solvents. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2019000101601 |
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| Nogueira,Alessandro; Guyot,Sylvain; Marnet,Nathalie; Lequéré,Jean Michel; Drilleau,Jean-Francoise; Wosiacki,Gilvan. |
| The objective of this work was to study the effect of alcoholic fermentation on the content of phenol compounds of five cider apple varieties. The initial content in the apple juice samples, as determined by HPLC, varied from 188.4 to 2776.17 m mg.L-1. In three of them (DC, PJ, GU), the total phenol compounds remained unaffected by fermentation. However, in two (DM, KE), the final values were lower (55 and 313 mg.L-1). In these apple cider, the values of caffeic acid increased from 6.6 mg.L-1 to 41.8 mg.L-1. The catechin content increased during the process, approximately 13 mg.L-1 independent of the variety. The other phenols class did not present any modifications due to the alcoholic fermentation, maintaining the phenolic compounds of original clarified... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cider; Fermentation alcoholic; Polyphenols. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000500020 |
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| SANTOS,JOãO L.A.; BISPO,VANDERSON S.; B.C. FILHO,ADRIANO; PINTO,ISABELLA F.D.; DANTAS,LUCAS S.; VASCONCELOS,DAIANE F.; ABREU,FABíULA F.; MELO,DANILO A.; MATOS,ISAAC A.; FREITAS,FLORêNCIO P.; GOMES,OSMAR F.; MEDEIROS,MARISA H.G.; MATOS,HUMBERTO R.. |
| Coconut water contains several uncharacterized substances and is widely used in the human consumption. In this paper we detected and quantified ascorbic acid and caffeic acid and total phenolics in several varieties of coconut using HPLS-MS-MS (25.8 ± 0.6 µg-mL and 1.078 ± 0.013 µg-mL and 99.7 µg-mL, respectively, in the green dwarf coconut water, or 10 mg and 539 µg and 39.8 mg for units of coconut consumed, 500 ± 50 mL). The antioxidant potential of four coconut varieties (green dwarf, yellow dwarf, red dwarf and yellow Malaysian) was compared with two industrialized coconut waters and the lyophilized water of the green dwarf variety. All varieties were effective in scavenging the DPPH radical (IC50=73 µL) and oxide nitric (0.1 mL with an IP of 29.9%) as... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidant activity; Ascorbic acid; Caffeic acid; Cocos nucifera; Polyphenols. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000401235 |
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| Danciu,Corina; Vlaia,Lavinia; Fetea,Florinela; Hancianu,Monica; Coricovac,Dorina E; Ciurlea,Sorina A; M Şoica,Codruţa; Marincu,Iosif; Vlaia,Vicentiu; Dehelean,Cristina A; Trandafirescu,Cristina. |
| BACKGROUND: Curcuma longa Linnaeus and Zingiber officinale Roscoe are two main representatives ofZingiberaceae family studied for a wide range of therapeutic properties, including: antioxidant, anti-inflammatory, anti-angiogenic, antibacterial, analgesic, immunomodulatory, proapoptotic, anti-human immunodeficiency virus properties and anticancer effects. This study was aimed to analyse the ethanolic extracts of Curcuma rhizome (Curcuma longa Linnaeus) and Zingiber rhizome (Zingiber officinale Roscoe) in terms of polyphenols, antioxidant activity and anti-melanoma potential employing the B164A5 murine melanoma cell line. RESULTS: In order to evaluate the total content of polyphenols we used Folin-Ciocâlteu method. The antioxidant activity of the two... |
| Tipo: Journal article |
Palavras-chave: Curcuma longa Linnaeus; Zingiber officinale Roscoe; Polyphenols; Antioxidant; Melanoma. |
| Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100001 |
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